Self-Assembling Peptide Hydrogels as Functional Tools to Tackle Intervertebral Disc Degeneration
Low back pain (LBP), caused by intervertebral disc (IVD) degeneration, is a major contributor to global disability.In its healthy state, the IVD is a tough and well-hydrated tissue, able to act as a shock absorber along the spine.During degeneration, the IVD is hit by a cell-driven cascade of events, which progressively lead to extracellular matrix